PPA T=100 - 150°C;

暂无反应条件数据

1: 68 percent / sodium hydrogen sulfite, 20 percent aq. HCl / 14 h / 90 °C 2: 41 percent / Br2 / CHCl3 / 2.5 h / Heating View Scheme

hydrogenchloride; nitrous acid methyl ester; sulfur dioxide; copper dichloride in methanol; 1,2-dichloro-ethane T=0 - 10°C; 3.5 h;

1: With sulfuric acid T=40°C; 0.5 h; 2: With 1,3-dibromo-5,5-dimethyl-hydantoin in sulfuric acid T=0 - 5°C; 1.5 h; Product distribution / selectivity;

triethylamine in dichloromethane T=20°C; 1 h;

1: With acetic acid T=20°C; 2: With N-bromosuccinmide in acetic acid T=0 - 5°C;

1: 85 percent / hydroxylamine hydrochloride; sodium sulfate; aq. HCl / 55 °C 2: 70 percent / conc. sulfuric acid / 55 - 80 °C View Scheme

T=20 - 165°C; neat (no solvent);

1.1: sodium hydride / ethylene glycol dimethyl ether; mineral oil / -5 - 20 °C 1.2: 3.5 h / 20 °C / Reflux 2.1: sec.-butyllithium / cyclohexane; tetrahydrofuran / 1 h / -78 °C 2.2: 0.67 h / -78 °C 3.1: triethylamine / copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride / 0.5 h / 20 °C 3.2: 1.5 h / 20 °C 4.1: potassium hydroxide; tert-butyl alcohol / 2 h / 80 °C View Scheme