5-(1H-吲哚-3-甲基)-1,3,4-噻二唑-2-胺合成路线 （共 9 条）
反应条件
sulfuric acid 0.166667 h; Heating;
参考文献
Kelarev, V. I.; Karakhanov, R. A.; Gasanov, S. Sh.; Morozova, G. V.; Kuatbekova, K. P.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 2.2 p. 323 - 329
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 2 p. 388 - 395
反应条件
trifluoroacetic acid T=60°C; Condensation; cyclization; 6 h;
参考文献
Ram, Vishnu Ji; Nath, Mahendra
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1997 , vol. 36, # 5 p. 394 - 398
反应条件
1: 65 percent / K2CO3 / acetone / 24 h / Heating 2: 70 percent / methanol / 15 h / Heating 3: 70 percent / H2SO4 / 20 °C View Scheme
参考文献
Sharma, Shalabh; Srivastava, Virendra Kishor; Kumar, Ashok
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 12 p. 2647 - 2654
反应条件
1: 70 percent / methanol / 15 h / Heating 2: 70 percent / H2SO4 / 20 °C View Scheme
参考文献
Sharma, Shalabh; Srivastava, Virendra Kishor; Kumar, Ashok
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2002 , vol. 41, # 12 p. 2647 - 2654
反应条件
in methanol 4 h; Heating;
参考文献
Kelarev, V. I.; Karakhanov, R. A.; Gasanov, S. Sh.; Morozova, G. V.; Kuatbekova, K. P.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 2.2 p. 323 - 329
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 2 p. 388 - 395
反应条件
1: K2CO3 / acetone 2: TFA View Scheme
参考文献
Ram, Vishnu Ji; Nath, Mahendra
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1997 , vol. 36, # 5 p. 394 - 398
反应条件
1: hydrogenchloride; hydrazine hydrate / ethanol 3: phosphoric acid View Scheme
参考文献
Rajak, Harish; Behera, Chinmay Kumar; Pawar, Rajesh Singh; Singour, Pradeep Kumar; Kharya, Murli Dhar
Acta Poloniae Pharmaceutica - Drug Research, 2010 , vol. 67, # 5 p. 503 - 510
反应条件
1: 55 percent / aq. HCl / 4 h / Heating 2: 71 percent / conc. H2SO4 / 0.17 h / Heating View Scheme
参考文献
Kelarev, V. I.; Karakhanov, R. A.; Gasanov, S. Sh.; Morozova, G. V.; Kuatbekova, K. P.
Russian Journal of Organic Chemistry, 1993 , vol. 29, # 2.2 p. 323 - 329
Zhurnal Organicheskoi Khimii, 1993 , vol. 29, # 2 p. 388 - 395
反应条件
trifluoroacetic acid Condensation; cyclization; elimination;
参考文献
Ram, Vishnu Ji; Nath, Mahendra
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1997 , vol. 36, # 5 p. 394 - 398
