1-(2,6-二氯苯基)-1,3-二氢-2H-吲哚-2-酮合成路线 (共 24 条)
反应条件
aluminium trichloride 1.) 145-150 deg C, 2.) 162-168 deg C, 2 h;
参考文献
Predvoditeleva, G. S.; Kartseva, T. V.; Oleshko, O. N.; Shvedov, V. I.; Syubaev, R. D.; et al.
Pharmaceutical Chemistry Journal, 1987 , vol. 21, # 4 p. 275 - 278
Khimiko-Farmatsevticheskii Zhurnal, 1987 , vol. 21, # 4 p. 441 - 445
反应条件
toluene-4-sulfonic acid in ethanol Cyclization;
参考文献
Khalaj; Amanlou; Jorjani
Pharmacy and Pharmacology Communications, 1998 , vol. 4, # 4 p. 201 - 203
反应条件
toluene-4-sulfonic acid in ethanol Cyclization;
参考文献
Khalaj; Amanlou; Jorjani
Pharmacy and Pharmacology Communications, 1998 , vol. 4, # 4 p. 201 - 203
反应条件
toluene-4-sulfonic acid in ethanol Cyclization;
参考文献
Khalaj; Amanlou; Jorjani
Pharmacy and Pharmacology Communications, 1998 , vol. 4, # 4 p. 201 - 203
反应条件
1: 85.5 percent / NaOH / propan-2-ol; H2O / 6.5 h / Heating 2: 78 percent / quinoline / 1 h / Heating View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 29, # 2 p. 100 - 105
Khimiko-Farmatsevticheskii Zhurnal, , vol. 29, # 2 p. 22 - 26
反应条件
1: sodium 2-[(2,6-dichlorophenyl)-amino]phenyl-acetate With β-cyclodextrin complexation; 2: With water T=19.85°C; Cyclization; oxidation; 17532 h; 3: methanol Esterification;
参考文献
Pharmazie, , vol. 54, # 12 p. 943 - 944
反应条件
water T=19.85°C; Decarboxylation; oxidation, cyclization, esterification; 17532 h; KineticsProduct distribution; Further Variations:rel. humidity; complexed with β-cyclodextrin;
参考文献
Pharmazie, , vol. 54, # 12 p. 943 - 944
反应条件
in phosphate buffer T=45°C; KineticsThermodynamic data; Further Variations:pH-valuesTemperatures;
参考文献
Pharmazie, , vol. 58, # 9 p. 631 - 635
反应条件
T=79.85°C; Decomposition; 17532 h; KineticsActivation energyThermodynamic data; Further Variations:Temperatures;
参考文献
Journal of Pharmacy and Pharmacology, , vol. 51, # 11 p. 1213 - 1218
反应条件
1: 77.3 percent / POCl3/DMF / CHCl3 / 6 h 2: 36.5 percent / piperidine / ethanol / 1 h View Scheme
参考文献
Pharmaceutical Chemistry Journal, , vol. 21, # 4 p. 275 - 278
Khimiko-Farmatsevticheskii Zhurnal, , vol. 21, # 4 p. 441 - 445