1: 91 percent / anhyd. potassium carbonate / dimethylformamide / 20 h / 130 °C 2: 99 percent / 70percent aq. perchloric acid / tetrahydrofuran; H2O / 1.) 0 deg C, 10 min, 2.) RT, 1 d View Scheme

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '605283', constants.ctx, '0')">triethylamine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=0&deg;C;&nbsp;3&nbsp;h;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 2 steps<br /> </b>1: 91 percent / thionyl chloride / heptane / 1.) 0 deg C, 10 min, 2.) RT, 10 min, 3.) reflux, 1 h<br />2: 96 percent / triethylamine / CH₂Cl₂ / 3 h / 0 &deg;C<br /> <br /> &nbsp;