4-甲氧基苄基丙二酸二甲酯合成路线 （共 5 条）
反应条件
hydrogen; palladium on activated charcoal in methanol
参考文献
Han, Jeng Liang; Ong, Chi Wi
Tetrahedron, 2005 , vol. 61, # 6 p. 1501 - 1507
反应条件
1: (4-methoxyphenyl)methanol With trifluoromethylsulfonic anhydride; bis-(phenyl)-sulfoxide; N,N,N',N'-tetra-methylnaphthalene-1,8-diamine in toluene T=-78°C; 2: sodium salt of dimethylmalonate in tetrahydrofuran; toluene T=-78 - 20°C;
参考文献
Takuwa, Tomofumi; Minowa, Tomofumi; Fujisawa, Hidehiko; Mukaiyama, Teruaki
Chemical and Pharmaceutical Bulletin, 2005 , vol. 53, # 5 p. 476 - 480
反应条件
1: With potassium tert-butylate; dirhodium tetraacetate in dichloromethane T=20°C; 2: With trimethylamine-N-oxide
参考文献
Han, Jeng Liang; Ong, Chi Wi
Tetrahedron, 2005 , vol. 61, # 6 p. 1501 - 1507
反应条件
1.1: potassium t-butoxide / Rh2(OAc)4 / CH2Cl2 / 20 °C 1.2: trimethylamine N-oxide 2.1: 100 percent / H2 / Pd/C / methanol View Scheme
参考文献
Han, Jeng Liang; Ong, Chi Wi
Tetrahedron, 2005 , vol. 61, # 6 p. 1501 - 1507
反应条件
1: piperidine; acetic acid / benzene / 4 h / |Reflux; |Dean-Stark 2: palladium 10 on activated carbon; hydrogen / methanol / 1 h / 20 °C View Scheme
参考文献
Mohite, Amar R.; Bhat, Ramakrishna G.
Organic Letters, 2013 , vol. 15, # 17 p. 4564 - 4567
