(5-甲基-3-异恶唑)甲胺合成路线 （共 9 条）
反应条件
sodium tetrahydroborate; sodium borohydride; triethylamine in isopropyl alcohol; citric acid
参考文献
Masciadri, Raffaello; Thomas, Andrew William; Wichmann, Juergen
Patent: US2003/55042 A1, 2003 ;
反应条件
sodium tetrahydroborate; TEA; 1,3-dimercaptopropane in isopropyl alcohol 24 h; Ambient temperature;
参考文献
Pei; Wickhan
Tetrahedron Letters, 1993 , vol. 34, # 47 p. 7509 - 7512
反应条件
1: 65 percent / Ph3PBr2 / CH2Cl2 / 1 h / Ambient temperature 2: 84 percent / NaN3 / acetone / 24 h / Ambient temperature 3: 98 percent / NaBH4, TEA / HS(CH2)3SH / propan-2-ol / 24 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 47 p. 7509 - 7512
反应条件
1: 60 percent / LiAlH4 / tetrahydrofuran / 0.5 h / -78 °C 2: 65 percent / Ph3PBr2 / CH2Cl2 / 1 h / Ambient temperature 3: 84 percent / NaN3 / acetone / 24 h / Ambient temperature 4: 98 percent / NaBH4, TEA / HS(CH2)3SH / propan-2-ol / 24 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 47 p. 7509 - 7512
反应条件
1: 84 percent / NaN3 / acetone / 24 h / Ambient temperature 2: 98 percent / NaBH4, TEA / HS(CH2)3SH / propan-2-ol / 24 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 47 p. 7509 - 7512
反应条件
1: 74 percent / NH2OH*HCl / ethanol / 2 h / Heating 2: 60 percent / LiAlH4 / tetrahydrofuran / 0.5 h / -78 °C 3: 65 percent / Ph3PBr2 / CH2Cl2 / 1 h / Ambient temperature 4: 84 percent / NaN3 / acetone / 24 h / Ambient temperature 5: 98 percent / NaBH4, TEA / HS(CH2)3SH / propan-2-ol / 24 h / Ambient temperature View Scheme
参考文献
Tetrahedron Letters, , vol. 34, # 47 p. 7509 - 7512
反应条件
hydrogenchloride; diethyl ether; tin(ll) chloride
参考文献
Gazzetta Chimica Italiana, , vol. 68, p. 625,635
反应条件
1: P2O5 2: SnCl2; HCl; diethyl ether View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 68, p. 625,635
反应条件
1: aqueous NH3 2: P2O5 3: SnCl2; HCl; diethyl ether View Scheme
参考文献
Gazzetta Chimica Italiana, , vol. 68, p. 625,635
