hydrogen; (R)-[RuCl2(BINAP)]n in ethanol T=95 - 105°C; P=67506.8 - 75007.5 Torr; 0.666667 - 480 h; Conversion of starting material;

1: With diethyl methoxy borane in tetrahydrofuran; methanol T=-70°C; Prasad's (syn-selective) reduction; 0.333333 h; 2: With sodium tetrahydroborate in tetrahydrofuran; methanol T=-70°C; 3 h;

1: With diethyl methoxy borane in tetrahydrofuran; methanol T=-70°C; 0.333333 h; 2: With sodium tetrahydroborate in tetrahydrofuran; methanol T=-70°C; 3 h; 3: With dihydrogen peroxide in tetrahydrofuran T=0 - 20°C; pH=9; 0.5 h; Further stages.;

1.1: NaH / tetrahydrofuran / 0.17 h 1.2: n-BuLi / tetrahydrofuran; hexane / 0.17 h / -10 °C 1.3: 58 percent / tetrahydrofuran; hexane / 1.5 h / -60 - -30 °C 2.1: 72 percent / NaDP(1+); Lactobacillus brevis alcohol dehydrogenase / propan-2-ol; various solvent(s) / 14 h / 20 °C / pH 5.5 3.1: B(OMe)Et2 / tetrahydrofuran; methanol / 0.33 h / -70 °C 3.2: NaBH4 / tetrahydrofuran; methanol / 3 h / -70 °C 3.3: 12.8 g / aq. H2O2 / tetrahydrofuran / 0.5 h / 0 - 20 °C / pH 9 View Scheme

camphor-10-sulfonic acid in acetone T=25°C; 1.5 h;