5-甲基-1,3-二苯-1H-吡唑-4-羧酸合成路线 （共 13 条）
反应条件
sodium hydroxide in methanol 4 h; Reflux;
参考文献
Ningaiah, Srikantamurthy; Bhadraiah, Umesha K.; Doddaramappa, Shridevi D.; Keshavamurthy, Shubakara; Javarasetty, Chethan
Bioorganic and Medicinal Chemistry Letters, 2014 , vol. 24, # 1 p. 245 - 248
反应条件
1: zinc chloride / 125 - 130 °C 2: sodium ethylate View Scheme
参考文献
Minunni
Atti della Accademia Nazionale dei Lincei, Classe di Scienze Fisiche, Matematiche e Naturali, Rendiconti, 1905 , vol. <5> 14 II, p. 418
Gazzetta Chimica Italiana, 1925 , vol. 55, p. 535
反应条件
1: aqueous KOH 2: ethanolic KOH / 150 °C View Scheme
参考文献
Fusco; Justoni
Gazzetta Chimica Italiana, 1937 , vol. 67, p. 3,7,8
反应条件
2: alcoholic KOH-solution View Scheme
参考文献
Knorr; Blank
Chemische Berichte, 1885 , vol. 18, p. 933
反应条件
2: alcoholic KOH-solution View Scheme
参考文献
Knorr; Blank
Chemische Berichte, 1885 , vol. 18, p. 933
反应条件
1: SOCl2 / 1 h / Heating 2: 67.8 percent / 1,2-dichloro-ethane / Ambient temperature View Scheme
参考文献
Zagorevskii, V. A.; Vlasova, N. V.; Zykov, D. A.; Kirsanova, Z. D.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 8 p. 684 - 689
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 8 p. 966 - 971
反应条件
1: SOCl2 / 1 h / Heating 2: 80 percent / 1,2-dichloro-ethane / Ambient temperature View Scheme
参考文献
Zagorevskii, V. A.; Vlasova, N. V.; Zykov, D. A.; Kirsanova, Z. D.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 8 p. 684 - 689
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 8 p. 966 - 971
反应条件
1: SOCl2 / 1 h / Heating 2: 58.5 percent / 1,2-dichloro-ethane / Ambient temperature View Scheme
参考文献
Zagorevskii, V. A.; Vlasova, N. V.; Zykov, D. A.; Kirsanova, Z. D.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 8 p. 684 - 689
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 8 p. 966 - 971
反应条件
1: SOCl2 / 1 h / Heating 2: 86.2 percent / 1,2-dichloro-ethane / Ambient temperature View Scheme
参考文献
Zagorevskii, V. A.; Vlasova, N. V.; Zykov, D. A.; Kirsanova, Z. D.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 8 p. 684 - 689
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 8 p. 966 - 971
反应条件
1: SOCl2 / 1 h / Heating 2: 49 percent / 1,2-dichloro-ethane / Ambient temperature View Scheme
参考文献
Zagorevskii, V. A.; Vlasova, N. V.; Zykov, D. A.; Kirsanova, Z. D.
Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 8 p. 684 - 689
Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 8 p. 966 - 971
