1: 1.) NaH, 2.) N-butyllithium 2: 1.) NaH / 1.) THF, -78 deg C, 2.) THF, from -78 deg C to RT 3: MeCu / tetrahydrofuran / 3 h / -25 °C 4: DIBAL / diethyl ether; hexane / 2 h / 0 °C View Scheme

n-butyllithium; sodium hydride Yield given. Multistep reaction;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '103233', constants.ctx, '0')">pyridine</a>&nbsp;<b>in</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '1730800', constants.ctx, '0')">dichloromethane</a> <br />T=-50 - -40&deg;C;&nbsp;0.25&nbsp;h;&nbsp;<br /> &nbsp;