(1R,10R,11S)-11-羟基-4-甲基-8,13-二氧杂-2,6-二氮杂三环[8.2.1.02,7]十三-3,6-二烯-5-酮合成路线 （共 7 条）
反应条件
1,8-diazabicyclo[5.4.0]undec-7-ene in acetonitrile 4.5 h; Heating;
参考文献
Jurczyk, Simona C.; Kodra, Janos T.; David Rozzell; Benner, Steven A.; Battersby, Thomas R.
Helvetica Chimica Acta, 1998 , vol. 81, # 5 p. 793 - 811
反应条件
1: in acetonitrile T=20°C; Inert atmosphere; 2: With DOWEX AG-50W column (NH4+) form in water; acetonitrile Inert atmosphere;
参考文献
Liang, Fengting; Jain, Nidhi; Hutchens, Troy; Shock, David D.; Beard, William A.; Wilson, Samuel H.; Chiarelli, M. Paul; Cho, Bongsup P.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 20 p. 6460 - 6470
反应条件
silver(I) acetate; acetonitrile
参考文献
Michelson; Todd
Journal of the Chemical Society, 1955 , p. 816,822
反应条件
1: pyridine / Behandeln des Reaktionsprodukts mit wss.-methanol.NH3 2: NaI 3: silver acetate; acetonitrile View Scheme
参考文献
Michelson; Todd
Journal of the Chemical Society, 1955 , p. 816,822
反应条件
pyridine; p-toluenesulfonyl chloride Product distribution / selectivity;
参考文献
CTI PET Systems, Inc.
Patent: US2005/131224 A1, 2005 ;
Location in patent: Sheet 3/3 ;
反应条件
ethylenediaminetetraacetic acid; sodium salt of phosphorous acid; sodium chloride in water T=37°C; pH=7.0; 6 h;
参考文献
Liang, Fengting; Jain, Nidhi; Hutchens, Troy; Shock, David D.; Beard, William A.; Wilson, Samuel H.; Chiarelli, M. Paul; Cho, Bongsup P.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 20 p. 6460 - 6470
反应条件
sodium hydroxide; water T=37°C; 0.5 h;
参考文献
Liang, Fengting; Jain, Nidhi; Hutchens, Troy; Shock, David D.; Beard, William A.; Wilson, Samuel H.; Chiarelli, M. Paul; Cho, Bongsup P.
Journal of Medicinal Chemistry, 2008 , vol. 51, # 20 p. 6460 - 6470
