3-氯-2,4-二氟苯甲酸合成路线 (共 13 条)
反应条件
in dichloromethane; N,N-dimethyl-formamide
参考文献
The Procter and Gamble Co.
Patent: US6329391 B1, 2001 ;
反应条件
sodium hydroxide; zinc 2 h; Heating;
参考文献
Heiss, Christophe; Rausis, Thierry; Schlosser, Manfred
Synthesis, 2005 , # 4 art. no. T11504SS, p. 617 - 621
反应条件
1: With dimethylsulfide borane complex in tetrahydrofuran
T=0 - 20°C; 14 h;
2: With water; sodium carbonate in tetrahydrofuran
T=0°C;
参考文献
AMGEN INC.
Patent: WO2007/61670 A1, 2007 ;
Location in patent: Page/Page column 178-179 ;
WO 2007/061670 A1