sodium hydroxide in 1,4-dioxane 18 h; Ambient temperature;

1.1: KF / dimethylformamide / 0.25 h / 20 °C 1.2: 66 percent / dimethylformamide / 6 h / 60 °C 2.1: 70 percent / aq. LiOH / methanol / 12 h View Scheme