3-(环戊氧基)-4-甲氧基苯胺合成路线 （共 12 条）
反应条件
hydrogen; palladium 10 on activated carbon in ethanol 4 h;
参考文献
MEMORY PHARMACEUTICALS CORPORATION
Patent: WO2004/9552 A1, 2004 ;
Location in patent: Page 54-55 ;
WO 2004/009552 A1
参考文献
MEMORY PHARMACEUTICALS CORP.
Patent: US2002/151566 A1, 2002 ;
US 20020151566 A1
反应条件
potassium iodide in 1,4-dioxane; water; ethyl acetate; N,N-dimethyl-formamide
参考文献
Rhone-Poulenc Rorer Limited
Patent: US5935978 A1, 1999 ;
US 5935978 A
Title/Abstract Full Text Show Details
Rhone-Poulenc Rorer Limited
Patent: US5679696 A1, 1997 ;
参考文献
Nikken Chemicals Co., Ltd.
Patent: US6235736 B1, 2001 ;
反应条件
1: 98 percent / K2CO3 / acetone / 24 h / Heating 2: H2 / Pd/C / ethyl acetate / 10 h / 20 °C View Scheme
参考文献
Garcia, Ariel L. L.; Carpes, Marcos J. S.; De Oca, Antonio C. B. M.; Dos Santos, Marco A. G.; Santana, Cesar C.; Correia, Carlos Roque D.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1050 - 1053
反应条件
1: 98 percent / K2CO3 / acetone / 24 h / Heating 2: H2 / Pd/C / ethyl acetate / 10 h / 20 °C View Scheme
参考文献
Garcia, Ariel L. L.; Carpes, Marcos J. S.; De Oca, Antonio C. B. M.; Dos Santos, Marco A. G.; Santana, Cesar C.; Correia, Carlos Roque D.
Journal of Organic Chemistry, 2005 , vol. 70, # 3 p. 1050 - 1053
参考文献
Nikken Chemicals Co., Ltd.
Patent: US6235736 B1, 2001 ;
反应条件
hydrogenchloride; water in ethanol T=80°C; 5 h; Inert atmosphere;
参考文献
Schmidt, Bernd; Elizarov, Nelli; Berger, Rene; Petersen, Monibh.
Synthesis (Germany), 2013 , vol. 45, # 9 art. no. SS-2013-T0092-OP, p. 1174 - 1180
反应条件
1: sodium hydrogencarbonate / methanol / 2 h / 20 °C / |Inert atmosphere 2: potassium iodide; potassium carbonate / N,N-dimethyl-formamide / 6 h / 100 °C / |Inert atmosphere 3: water; hydrogenchloride / ethanol / 5 h / 80 °C / |Inert atmosphere View Scheme
参考文献
Schmidt, Bernd; Elizarov, Nelli; Berger, Rene; Petersen, Monibh.
Synthesis (Germany), 2013 , vol. 45, # 9 art. no. SS-2013-T0092-OP, p. 1174 - 1180
反应条件
1: 24 h / 20 °C / |Inert atmosphere 2: sodium hydrogencarbonate / methanol / 2 h / 20 °C / |Inert atmosphere 3: potassium iodide; potassium carbonate / N,N-dimethyl-formamide / 6 h / 100 °C / |Inert atmosphere 4: water; hydrogenchloride / ethanol / 5 h / 80 °C / |Inert atmosphere View Scheme
参考文献
Schmidt, Bernd; Elizarov, Nelli; Berger, Rene; Petersen, Monibh.
Synthesis (Germany), 2013 , vol. 45, # 9 art. no. SS-2013-T0092-OP, p. 1174 - 1180
