4'-(羟基甲基)-4-联苯甲腈合成路线 （共 4 条）
反应条件
methanol; sodium tetrahydroborate T=20°C;
参考文献
SMITHKLINE BEECHAM CORPORATION; BOUILLOT, Anne Marie Jeanne; DODIC, Nerina; GELLIBERT, Francoise Jeanne; MIRGUET, Olivier
Patent: WO2010/15653 A1, 2010 ;
Location in patent: Page/Page column 38 ;
WO 2010/015653 A1
反应条件
palladium diacetate; potassium carbonate in methanol T=80°C; Suzuki-Miyaura cross-coupling reaction; 0.0833333 h; Microwave irradiation;
参考文献
Park, Young Hee; Ahn, Hong Ryul; Canturk, Belgin; Jeon, Sang Ii; Lee, Seokjoon; Kang, Heonjoong; Molander, Gary A.; Ham, Jungyeob
Organic Letters, 2008 , vol. 10, # 6 p. 1215 - 1218
反应条件
potassium carbonate in methanol; water T=40 - 45°C; Suzuki Coupling; 3 h;
参考文献
Maity, Indrajit; Rasale, Dnyaneshwar B.; Das, Apurba K.
RSC Advances, 2014 , vol. 4, # 6 p. 2984 - 2988
反应条件
phosphorus tribromide in dichloromethane T=0 - 20°C;
参考文献
SMITHKLINE BEECHAM CORPORATION; BOUILLOT, Anne Marie Jeanne; DODIC, Nerina; GELLIBERT, Francoise Jeanne; MIRGUET, Olivier
Patent: WO2010/15652 A2, 2010 ;
Location in patent: Page/Page column 47 ;
WO 2010/015652 A2
