3-(二甲基氨基)-2,2-二甲基-1-苯基-1-丙酮合成路线 （共 10 条）
反应条件
4-(N,N-dimethlyamino)pyridine; [2,2']bipyridinyl; AZADO; copper(l) chloride in acetonitrile T=20°C; 2.5 h; chemoselective reaction;
参考文献
Sasano, Yusuke; Nagasawa, Shota; Yamazaki, Mai; Shibuya, Masatoshi; Park, Jaiwook; Iwabuchi, Yoshiharu
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3236 - 3240
Angew. Chem., 2014 , vol. 126, # 12 p. 3300 - 3304,5
参考文献
Coward,J.K.; Bruice,T.C.
Journal of the American Chemical Society, 1969 , vol. 91, p. 5339 - 5345
反应条件
1.1: isopropyl alcohol / 46 h / |Inert atmosphere; |Reflux 1.2: 0.75 h / 0 °C / |Inert atmosphere 2.1: 4-(N,N-dimethlyamino)pyridine; [2,2']bipyridinyl; AZADO; copper(l) chloride / acetonitrile / 2.5 h / 20 °C View Scheme
参考文献
Sasano, Yusuke; Nagasawa, Shota; Yamazaki, Mai; Shibuya, Masatoshi; Park, Jaiwook; Iwabuchi, Yoshiharu
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3236 - 3240
Angew. Chem., 2014 , vol. 126, # 12 p. 3300 - 3304,5
参考文献
Daruwala,A.B. et al.
Journal of Medicinal Chemistry, 1974 , vol. 17, # 8 p. 819 - 824
Full Text View citing articles Show Details
Snyder; Brewster
Journal of the American Chemical Society, 1949 , vol. 71, p. 1058
参考文献
Anderson,A.G.; Wills,M.T.
Journal of Organic Chemistry, 1968 , vol. 33, # 2 p. 536 - 541
反应条件
in methanol; dichloromethane 48 h; 9 kbar;
参考文献
Matsumoto, Kiyoshi; Hashimoto, Shiro; Otani, Shinichi; Amita, Fujitsugu; Osugi, Jiro
Synthetic Communications, 1984 , vol. 14, # 6 p. 585 - 590
反应条件
aluminium trichloride
参考文献
Merck,E.
Patent: DE629054 , 1934 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 23, p. 584
Full Text Show Details
Merck and Co. Inc.
Patent: US2370015 , 1941 ;
参考文献
Snyder; Brewster
Journal of the American Chemical Society, 1949 , vol. 71, p. 1058
参考文献
Snyder; Brewster
Journal of the American Chemical Society, 1949 , vol. 71, p. 1058
反应条件
sodium tetrahydroborate in methanol 8 h; Heating;
参考文献
Avramova; Dryanovska; Ilarionov
Pharmazie, 1981 , vol. 36, # 6 p. 410 - 412
