6-(2-氟苯基)[1,3]二氧杂环戊并[4,5-g]喹啉-8(5H)-酮合成路线 （共 4 条）
反应条件
potassium tert-butylate; triethylamine in tetrahydrofuran; (2S)-N-methyl-1-phenylpropan-2-amine hydrate; tert-butyl alcohol
参考文献
The University of North Carolina at Chapel Hill
Patent: US6569870 B1, 2003 ;
反应条件
potassium tert-butylate in tert-butyl alcohol T=70°C; Yield given;
参考文献
Xia; Yang; Hackl; Hamel; Mauger; Wu; Lee
Journal of Medicinal Chemistry, 2001 , vol. 44, # 23 p. 3932 - 3936
反应条件
1: Et3N / tetrahydrofuran / 0 - 20 °C 2: potassium tert-butoxide / 2-methyl-propan-2-ol / 24 h / 70 °C View Scheme
参考文献
Li; Wang; Kuo; Wu; Lednicer; Lin; Hamel; Lee -
Journal of Medicinal Chemistry, 1994 , vol. 37, # 8 p. 1126 - 1135
反应条件
1: Et3N / tetrahydrofuran / 0 - 20 °C 2: potassium tert-butoxide / 2-methyl-propan-2-ol / 24 h / 70 °C View Scheme
参考文献
Li; Wang; Kuo; Wu; Lednicer; Lin; Hamel; Lee -
Journal of Medicinal Chemistry, 1994 , vol. 37, # 8 p. 1126 - 1135
