4-(N-苯甲酰基氨基)苯酚合成路线 （共 39 条）
反应条件
1: nitric acid / -10 - 0 °C 2: concentrated sulfuric acid View Scheme
参考文献
Reverdin; Deletra
Chemische Berichte, 1906 , vol. 39, p. 126
Bulletin de la Societe Chimique de France, 1906 , vol. <3>35, p. 306
反应条件
1: concentrated sulfuric acid / 120 °C 2: concentrated sulfuric acid; nitric acid / 0 °C / dann bei 30grad 3: bei der Verseifung View Scheme
参考文献
Reverdin
Chemische Berichte, 1906 , vol. 39, p. 3794
Bulletin de la Societe Chimique de France, 1906 , vol. <3>35, p. 1256
Chem. Zentralbl., 1907 , vol. 78, # I p. 104
反应条件
1: 4-amino-phenol With triethylamine in N,N-dimethyl-formamide
T=0°C; 0.166667 h;
2: benzoyl chloride in N,N-dimethyl-formamide
T=0 - 20°C; 18 h;
参考文献
CHROMA THERAPEUTICS LTD
Patent: WO2006/117570 A1, 2006 ;
Location in patent: Page/Page column 23-25 ;
WO 2006/117570 A1
反应条件
potassium phosphate; tris-(dibenzylideneacetone)dipalladium(0) in tert-butyl alcohol
T=110°C; 24 h;
参考文献
Ikawa, Takashi; Barder, Timothy E.; Biscoe, Mark R.; Buchwald, Stephen L.
Journal of the American Chemical Society, 2007 , vol. 129, # 43 p. 13001 - 13007
反应条件
TEA; DBOP in various solvent(s)
2 h; Ambient temperature;
参考文献
Ueda; Mori
Bulletin of the Chemical Society of Japan, 1992 , vol. 65, # 6 p. 1636 - 1641
反应条件
1: 4-amino-phenol With triethylamine in N,N-dimethyl-formamide
T=0°C; 0.166667 h;
2: benzoyl chloride in N,N-dimethyl-formamide
T=20°C; 18.0833 h;
参考文献
CHROMA THERAPEUTICS LTD
Patent: WO2006/117567 A2, 2006 ;
Location in patent: Page/Page column 55 ;
反应条件
sodium lauryl sulfate in water; acetonitrile
0.0833333 h;
参考文献
Naik, Sarala; Bhattacharjya, Gitalee; Talukdar, Bandana; Patel, Bhisma K.
European Journal of Organic Chemistry, 2004 , # 6 p. 1254 - 1260
反应条件
trifluoroacetic acid; bis-[(trifluoroacetoxy)iodo]benzene in chloroform
T=20°C; 0.5 h;
参考文献
Itoh, Naoki; Sakamoto, Takeshi; Miyazawa, Etsuko; Kikugawa, Yasuo
Journal of Organic Chemistry, 2002 , vol. 67, # 21 p. 7424 - 7428
反应条件
1: 4-amino-phenol With n-butyllithium in tetrahydrofuran; hexane
T=20°C; 1 h;
2: benzoyl-protected allyl alcohol in tetrahydrofuran; hexane
T=20°C; 12 h;
参考文献
Faler, Catherine A.; Joullie, Madeleine M.
Tetrahedron Letters, 2006 , vol. 47, # 40 p. 7229 - 7231
反应条件
in various solvent(s)
T=15°C; 0.333333 h;
参考文献
Ueda, Mitsuru; Seki, Kouji; Imai, Yoshio
Synthesis, 1981 , # 12 p. 991 - 993
