hydrogenchloride; sodium carbonate in methanol

dihydrogen peroxide in tetrahydrofuran; water T=80°C; 2 h;

trichlorophosphate 2 h; Heating;

暂无反应条件数据

1: 6-trifluoromethyl-4-hydroxypyrimidine With oxalyl dichloride; N,N-dimethyl-formamide in ethyl acetate 2 h; Reflux; 2: ammonia in methanol T=70°C; 15 h; Sealed tube;

1: With trichlorophosphate 7 h; Heating / reflux; 2: With ammonia in water T=20°C;

1.1: 73 percent / phosphoric trichloride / 2 h / Heating 2.1: butyllithium / tetrahydrofuran; hexane / 0.75 h / -75 °C 2.2: tetrahydrofuran; hexane / -78 °C 2.3: 31 percent / aq.HCl / H2O / pH 2 3.1: 83 percent / hydrogen; triethylamine / palladium on charcoal / methanol / 2 h / 25 °C / 760 Torr View Scheme

1: 86 percent / bromine; potassium acetate / acetic acid / 2 h / 80 °C 2: 77 percent / phosphorus tribromide / 0.75 h / 150 °C View Scheme

1: 86 percent / bromine; potassium acetate / acetic acid / 2 h / 80 °C 2: 77 percent / phosphorus tribromide / 0.75 h / 150 °C 3: 72 percent / hydrazine monohydrate / ethanol View Scheme