hydrogenchloride in methanol Ambient temperature; Title compound not separated from byproducts;

<b>With</b>&nbsp; <a href="#" onclick="return RXDsubstances(event, this, '11342940', constants.ctx, '0')">sodium hydroxide</a>;&nbsp;<a href="#" onclick="return RXDsubstances(event, this, '746197', constants.ctx, '0')">trifluoroacetic anhydride</a> <br />&nbsp;1.) CH₂Cl₂, r.t., 4 h, 2.) MeOH, r.t., 6 h;&nbsp;&nbsp;Yield given. Multistep reaction;&nbsp;<br /> &nbsp;

<b>Multi-step reaction with 4 steps<br /> </b>1: 95 percent / molecular sieves 4 Angstroem / diethyl ether / 0.33 h / Ambient temperature<br />2: 95 percent / 1 h / 110 &deg;C<br />3: tetrahydrofuran / 1 h / -70 &deg;C<br />4: 1.) trifluoroacetic anhydride, 2.) 15percent aq. NaOH / 1.) CH₂Cl₂, r.t., 4 h, 2.) MeOH, r.t., 6 h<br /> <br /> &nbsp;