2,3-二氢-噻吩并[3,4-b]-1,4-二噁英-5,7-二羧酸二乙酯合成路线 (共 13 条)
反应条件
potassium carbonate in N,N-dimethyl-formamide T=160°C; Williamson Ether Synthesis; 0.333333 h; Microwave irradiation; Wavelength;
参考文献
Far Eastern New Century Corporation; Liang, Nai-Yun; Tsai, Hui-Shan; Ke, Ching-Wei; Jseng, Chin-Wan
Patent: EP2548875 A1, 2013 ;
Location in patent: Paragraph 0083-0088 ;
反应条件
tributylphosphine; diethylazodicarboxylate in tetrahydrofuran T=66°C; Mitsunobu reaction; 6 h;
参考文献
Zong, Kyukwan; Madrigal, Luis; Groenendaal; Reynolds, John R.
Chemical Communications, 2002 , # 21 p. 2498 - 2499
反应条件
in tetrahydrofuran; ethylene glycol
参考文献
AGFA-GEVAERT
Patent: US2003/162958 A1, 2003 ;
反应条件
in tetrahydrofuran; ethylene glycol
参考文献
AGFA-GEVAERT
Patent: US2003/162958 A1, 2003 ;
反应条件
Williamson reaction;
参考文献
Molcanov, Kresimir; Stolic, Ivana; Kovacevic, Goran; Kojic-Prodic, Biserka; Bajic, Miroslav
Journal of Molecular Structure, 2011 , vol. 987, # 1-3 p. 174 - 179
反应条件
sodium hydride; triethylamine in N,N-dimethyl-formamide Williamson synthesis; 5 h; Reflux;
参考文献
Zhang, Hua; Qian, Chao; Chen, Xin-Zhi
Journal of Chemical Research, 2011 , vol. 35, # 6 p. 339 - 340
反应条件
1.1: NaOEt / ethanol / 0.5 h 1.2: 66 percent / ethanol / 18 h / Heating 2.1: 43 percent / DEAD; Ph3P / tetrahydrofuran / 18 h / Heating View Scheme
参考文献
Far Eastern New Century Corporation; Liang, Nai-Yun; Tsai, Hui-Shan; Ke, Ching-Wei; Jseng, Chin-Wan
Patent: EP2548875 A1, 2013 ;
反应条件
sodium ethanolate 1.) ethanol, 1 h, reflux; 2.) 24 h, 110 deg C; Yield given. Multistep reaction. Yields of byproduct given;
参考文献
Holzer, W.; Schmid, E.; Slatin, C.
Monatshefte fuer Chemie, 1994 , vol. 125, # 11 p. 1287 - 1292
参考文献
Guha; Iyer
Journal of the Indian Institute of Science, 1938 , vol. <A> 21, p. 115,118
反应条件
1: 95 percent / KOH / ethanol / 3 h / Heating 2: 68 percent / CuO; quinoline / 5 h / 200 °C 3: NBS; AcOH / CH2Cl2 / 3 h / 0 °C View Scheme
参考文献
Spencer, Howard J.; Skabara, Peter J.; Giles, Mark; McCulloch, Iain; Coles, Simon J.; Hursthouse, Michael B.
Journal of Materials Chemistry, 2005 , vol. 15, # 45 p. 4783 - 4792