1-甲基-2-氧代-1,2-二氢吡啶-3-羧酸合成路线 （共 17 条）
反应条件
1: With methanol; lithium hydroxide; water in tetrahydrofuran T=20°C; 2 h; 2: With hydrogenchloride in tetrahydrofuran; methanol; water
参考文献
US2007/197537 A1, ;
Page/Page column 108 ;
US 20070197537 A1
反应条件
potassium hydroxide in methanol; water Methylation; 2 h; Heating;
参考文献
Sieburth, Scott McN.; McGee Jr., Kevin F.; Zhang, Fangning; Chen, Yanping
Journal of Organic Chemistry, 2000 , vol. 65, # 7 p. 1972 - 1977
反应条件
1: 2-oxy-pyridine-3-carboxylic acid With potassium hydroxide in methanol; water 0.25 h; Heating / reflux; 2: methyl iodide in methanol; water 2 h; Heating / reflux; 3: With hydrogenchloride in methanol; water
参考文献
WO2007/30061 A1, ;
Page/Page column 98-99 ;
WO 2007/030061 A1
反应条件
sodium hydroxide; dihydrogen peroxide in water T=35°C; 16 h;
参考文献
Becher, Jan; Johansen, Tea; Michael, Maged Aziz
Journal of Heterocyclic Chemistry, 1984 , vol. 21, # 1 p. 41 - 48
参考文献
Biochemical Journal, , vol. 43, p. 423,425
反应条件
potassium hydroxide in methanol; water Heating;
参考文献
Bulletin of the Chemical Society of Japan, , vol. 78, # 6 p. 1127 - 1131
反应条件
1: K3<Fe(CN)6>; aqueous KOH 2: aqueous NaOH View Scheme
参考文献
Biochemical Journal, , vol. 43, p. 423,425
反应条件
1: methanol 2: K3<Fe(CN)6>; aqueous KOH 3: aqueous NaOH View Scheme
参考文献
Biochemical Journal, , vol. 43, p. 423,425
参考文献
Doklady Akademii Nauk SSSR, , vol. 66, p. 647,649
Chem.Abstr., , p. 7024
反应条件
potassium chloride in water T=25°C; Rate constant;
参考文献
Australian Journal of Chemistry, , vol. 38, # 4 p. 637 - 641
