1.1: trifluoroacetic acid / acetonitrile; water / 6 h / Reflux 2.1: lithium hexamethyldisilazane; N2,N2-dimethyl-2-methyl-1,2-propanediamine / tetrahydrofuran / 3 h / -78 °C 2.2: 3 h / -78 °C 3.1: pyridine; trichlorophosphate / 12.5 h / 10 - 20 °C 3.2: 0 °C / pH 5.5 4.1: hydrogen / palladium 10 on activated carbon / methanol / 3102.97 Torr 5.1: n-butyllithium; N2,N2-dimethyl-2-methyl-1,2-propanediamine / tetrahydrofuran; tetrahydro-4H-pyran / 1.33 h / -78 °C 5.2: 1.33 h / -78 °C 5.3: -78 °C / pH 7 6.1: triethylamine / dichloromethane / -10 °C 7.1: tetra(n-butyl)ammonium hydrogensulfate; sodium azide / N,N-dimethyl-formamide / 36 h / 90 °C 8.1: triethylamine; hydrogen / palladium 10 on activated carbon / ethanol; water / 16 h / 3102.97 Torr 9.1: potassium hydroxide / water; tetrahydrofuran; methanol / 10 h / 0 °C 9.2: 10 h / 0 - 20 °C 10.1: triethylamine; 2-hydroxy-pyridine / 48 h / 90 °C 11.1: trifluoroacetic acid / dichloromethane / 3 h / 20 °C View Scheme

lithium aluminium tetrahydride in diethyl ether Ambient temperature;