异丙基-吡啶-2-基-胺双盐酸盐合成路线 （共 6 条）
反应条件
CuCN in tetrahydrofuran T=-50 - 20°C; Substitution; 2 h;
参考文献
Bernardi, Paolo; Dembech, Pasquale; Fabbri, Gaia; Ricci, Alfredo; Seconi, Giancarlo
Journal of Organic Chemistry, 1999 , vol. 64, # 2 p. 641 - 643
反应条件
trifluoroacetic acid in dichloromethane; water
参考文献
Krein, Douglas M.; Lowary, Todd L.
Journal of Organic Chemistry, 2002 , vol. 67, # 14 p. 4965 - 4967
反应条件
1: 98 percent / 2-methyl-propan-2-ol / 24 h / 25 °C 2: 74 percent / NaH / dimethylformamide / 1.5 h / 0 - 20 °C 3: 93 percent / TFA / CH2Cl2; H2O View Scheme
参考文献
Krein, Douglas M.; Lowary, Todd L.
Journal of Organic Chemistry, 2002 , vol. 67, # 14 p. 4965 - 4967
反应条件
1: 74 percent / NaH / dimethylformamide / 1.5 h / 0 - 20 °C 2: 93 percent / TFA / CH2Cl2; H2O View Scheme
参考文献
Krein, Douglas M.; Lowary, Todd L.
Journal of Organic Chemistry, 2002 , vol. 67, # 14 p. 4965 - 4967
参考文献
Pan, Shiguang; Matsuo, Yusuke; Endo, Kohei; Shibata, Takanori
Tetrahedron, 2012 , vol. 68, # 44 p. 9009 - 9015
参考文献
Schering-Kahlbaum A. G.
Patent: DE484835 ;
Fortschr. Teerfarbenfabr. Verw. Industriezweige, vol. 16, p. 2645
