4-(1H-吲哚-3-基)-5,6-二氢吡啶-1(2H)-羧酸叔丁酯合成路线 （共 3 条）
反应条件
potassium hydroxide in methanol T=60°C; 18 h; Product distribution / selectivity;
参考文献
MYREXIS, INC.; KUMAR, Dange Vijay; SLATTUM, Paul M.; YAGER, Kraig M.; SHENDEROVICH, Mark D.; TANGALLAPALLY, Rajendra; KIM, Se-Ho
Patent: WO2012/177782 A1, 2012 ;
Location in patent: Page/Page column 70 ;
WO 2012/177782 A1
反应条件
di-tert-butyl dicarbonate in methanol 12 h;
参考文献
SCHERING CORPORATION
Patent: WO2004/831 A1, 2003 ;
Location in patent: Page 39 ;
WO 2004/000831 A1
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Cole, Derek C.; Ellingboe, John W.; Lennox, William J.; Mazandarani, Hossein; Smith, Deborah L.; Stock, Joseph R.; Zhang, Guoming; Zhou, Ping; Schechter, Lee E.
Bioorganic and Medicinal Chemistry Letters, 2005 , vol. 15, # 2 p. 379 - 383
