4-(1H-吲哚-3-基)哌啶-1-甲酸叔丁酯合成路线 （共 8 条）
反应条件
ammonium formate; palladium 10 on activated carbon in methanol 20 h; Reflux;
参考文献
KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN Randamp;;D; reMYND; GRIFFIOEN, Gerard; VAN DOOREN, Tom; ROJAS DE LA PARRA, Veronica; MARCHAND, Arnaud; ALLASIA, Sara; KILONDA, Amuri; CHALTIN, Patrick
Patent: WO2010/142801 A1, 2010 ;
Location in patent: Page/Page column 201 ;
WO 2010/142801 A1
反应条件
potassium carbonate in tetrahydrofuran; water T=60°C; 27 h;
参考文献
US2009/318498 A1, ;
Page/Page column 11-12 ;
US 20090318498 A1
反应条件
1: in dichloromethane T=20°C; 1 h; 2: With sodium tris(acetoxy)borohydride in dichloromethane T=20°C; 24 h;
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 23, # 24 p. 6773 - 6776
反应条件
in tetrahydrofuran; water
反应条件
hydrogen; palladium on activated charcoal in ethanol
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 2 p. 379 - 383
反应条件
1: KOH / methanol / 60 °C 2: H2 / Pd/C / ethanol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 2 p. 379 - 383
反应条件
1: KOH / methanol / 60 °C 2: H2 / Pd/C / ethanol View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 2 p. 379 - 383
反应条件
hydrogenchloride in 1,4-dioxane
T=20°C; 2 h;
参考文献
KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN Randamp;;D; reMYND; GRIFFIOEN, Gerard; VAN DOOREN, Tom; ROJAS DE LA PARRA, Veronica; MARCHAND, Arnaud; ALLASIA, Sara; KILONDA, Amuri; CHALTIN, Patrick
Patent: WO2010/142801 A1, 2010 ;
Location in patent: Page/Page column 201 ;
WO 2010/142801 A1
