2-(4-氟苯基)-2,3-二氢-4(1H)-喹啉酮合成路线 （共 8 条）
反应条件
alumina supported CeCl3*7H2O-NaI T=70°C; aza-Michael reaction;
参考文献
Ahmed, Naseem; van Lier, Johan E.
Tetrahedron Letters, 2007 , vol. 48, # 1 p. 13 - 15
反应条件
L-proline in methanol T=20°C; 48 h;
参考文献
Chandrasekhar; Vijeender; Sridhar
Tetrahedron Letters, 2007 , vol. 48, # 28 p. 4935 - 4937
反应条件
hydrogenchloride in water 12 h; Reflux;
参考文献
Letters in Drug Design and Discovery, , vol. 10, # 4 p. 327 - 334
反应条件
SbCl3-impregnated silica gel T=100°C; intramolecular aza-Michael reaction; 0.166667 h; Neat (no solvent);
参考文献
Bhattacharya; Kundu, Pradip; Maiti, Gourhari
Synthetic Communications, 2010 , vol. 40, # 4 p. 476 - 481
反应条件
1: 59 percent / NaOH / ethanol / Ambient temperature 2: 90 percent / H3PO3 / acetic acid / Heating View Scheme
参考文献
South African Journal of Chemistry, , vol. 47, # 1 p. 21 - 25
反应条件
1: sodium hydroxide / methanol; water / 6 h / 20 °C 2: hydrogenchloride / water / 12 h / |Reflux View Scheme
参考文献
Archiv der Pharmazie, , vol. 346, # 1 p. 7 - 16
反应条件
1: 59 percent / NaOH / ethanol / Ambient temperature 2: 90 percent / H3PO3 / acetic acid / Heating View Scheme
参考文献
South African Journal of Chemistry, , vol. 47, # 1 p. 21 - 25
反应条件
1: ethylene glycol dimethyl ether; diethyl ether / 1 h / 0 °C 2: 4-(N,N-dimethlyamino)pyridine / 6 h / 70 °C 3: sodium hydroxide / methanol; water / 6 h / 20 °C 4: hydrogenchloride / water / 12 h / |Reflux View Scheme
参考文献
Archiv der Pharmazie, , vol. 346, # 1 p. 7 - 16
