2-氨基-3,6-二甲基苯甲酸合成路线 （共 13 条）
反应条件
1: trifluoroacetic acid, isoamyl nitrite / tetrahydrofuran / 1.5 h
2: 14.38 g / 1,2-dichloro-ethane / Heating
3: 69.16 percent / N-bromosuccinimide / CCl4 / Heating
View Scheme
参考文献
Wilcox, Charles F.; Farley, Erik N.
Journal of the American Chemical Society, 1984 , vol. 106, # 23 p. 7195 - 7200
反应条件
1: 26 percent / isoamyl nitrite / 1,2-dichloro-ethane; bis-(2-methoxy-ethyl) ether / 1.5 h / Heating
2: 58 percent / DDQ / chlorobenzene / 5 h / Heating
View Scheme
参考文献
Bell, Stephanie E. V.; Brown, Roger F. C.; Coulston, Karen J.; Eastwood, Frank W.
Australian Journal of Chemistry, 1994 , vol. 47, # 8 p. 1469 - 1482
反应条件
1: With trifluoroacetic acid; isopentyl nitrite in tetrahydrofuran
T=-10°C; 1.5 h;
2: in dichloromethane
1 h; Reflux;
参考文献
Christoph, Hilmar; Grunenberg, Joerg; Hopf, Henning; Dix, Ina; Jones, Peter G.; Scholtissek, Martin; Maier, Guenther
Chemistry - A European Journal, 2008 , vol. 14, # 18 p. 5604 - 5616
