1: 1.) 3-BuLi / 1.) THF, TMEDA, 2.) THF 2: NaOH / H2O 3: K2CO3 / acetone 4: NaH / tetrahydrofuran 5: CF3COOH / H2O 6: 85 percent / NaOAc / 4 h / 140 °C 7: 1.) CrO3, 2.) 48percent HBr / 1.) AcOH, View Scheme

1: 1.) 3-BuLi / 1.) THF, TMEDA, 2.) THF 2: NaOH / H2O View Scheme