(R)-4-(叔丁氧基)-2-((叔丁氧基羰基)氨基)-4-氧代丁酸合成路线 (共 1 条)
反应条件
1: (R)-2-amino-4-tert-butoxy-4-oxobutanoic acid in tetrahydrofuran; water T=0°C; 0.0833333 h; 2: di-tert-butyl dicarbonate With sodium carbonate in tetrahydrofuran; water T=20°C; 24 h;
参考文献
Henry, Luc; Leung, Ivanhoe K.H.; Claridge, Timothy D.W.; Schofield, Christopher J.
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 15 p. 4975 - 4978