N,3,4-三甲氧基-n-甲基苯甲酰胺合成路线 （共 5 条）
反应条件
triethylamine; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; palladium diacetate in toluene T=80°C; P=760 Torr; 15 h;
参考文献
Martinelli, Joseph R.; Watson, Donald A.; Freckmann, Dominique M. M.; Barder, Timothy E.; Buchwald, Stephen L.
Journal of Organic Chemistry, 2008 , vol. 73, # 18 p. 7102 - 7107
反应条件
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine in N,N-dimethyl-formamide T=20°C; 3 h;
参考文献
Hayashi, Yoshio; Yamazaki, Yuri; Sumikura, Makiko; Masuda, Yurika; Hayashi, Yoshiki; Yasui, Hiroyuki; Kiso, Yoshiaki; Chinen, Takumi; Usui, Takeo; Yakushiji, Fumika; Potts, Barbara; Neuteboom, Saskia; Palladino, Michael; Lloyd, George Kenneth
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 14 p. 4279 - 4289
反应条件
triethylamine; 1,1'-carbonyldiimidazole
参考文献
Lee, Ki-Ho; Park, Chun-Eung; Min, Kyung-Hyun; Shin, Yong-Je; Chung, Coo-Min; Kim, Hui-Ho; Yoon, Hae-Jeoung; Won-Kim; Ryu, Eun-Ju; Shin, Yu-Jin; Nam, Hyun-Sik; Cho, Jeong-Woo; Lee, Hee-Yoon
Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 18 p. 5567 - 5571
反应条件
in tetrahydrofuran T=-10°C;
参考文献
Kumar, Amit; Akula, Hari Kiran; Lakshman, Mahesh K.
European Journal of Organic Chemistry, 2010 , # 14 p. 2709 - 2715
反应条件
1: 85 percent / diethyl ether / 0.83 h / 0 - 20 °C
2: 81 percent / BF3*OEt2 / CH2Cl2 / 0.17 h / 0 °C
3: 1.) O3, 2.) Me2S / 1.) CH2Cl2, -78 deg C, 25 min, 2.) CH2Cl2
View Scheme
参考文献
Nagao, Yoshimitsu; Lee, Woo-Song; Kim, Kweon
Chemistry Letters, 1994 , # 2 p. 389 - 392
