potassium hydroxide; PEG-8000 T=150°C; 6 h; Yields of byproduct given;

potassium hydroxide in ethanol Heating;

chlorine in water; acetonitrile T=25°C; under HPLC conditions on a reversed-phase column with continuous eluant flow; competition reaction with other alkyl phenyl ethers for the investigation of the substrate selectivity; Product distribution;

1: HCl / acetic acid / 100 - 110 °C 2: dimethylsulfoxide / 35 - 40 °C 3: H2SO4 / Heating 4: NH2OH*HCl, NaOMe / methanol / Heating View Scheme

hydrogenchloride in acetic acid T=100 - 110°C;