1-(硫代苯甲酰基)哌啶合成路线 （共 35 条）
反应条件
1: 76 percent / benzene / standing overnight
2: 20.8 g / H2S (gas) / ethanol / 1.) -60 - 50 deg C, 13 hrs., 2.) -15 deg C, overnight
View Scheme
参考文献
Tomchin, A.B.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, p. 504 - 510
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 3 p. 589 - 595
反应条件
2: hydrogen sulfide / ethanol
3: sodium hydroxide
View Scheme
参考文献
Chen, Shoujun; Sun, Lijun; Koya, Keizo; Tatsuta, Noriaki; Xia, Zhiqiang; Korbut, Timothy; Du, Zhenjian; Wu, Jim; Liang, Guiqing; Jiang, Jun; Ono, Mitsunori; Zhou, Dan; Sonderfan, Andrew
Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 18 p. 5070 - 5076
反应条件
1: CH2Cl2 / 12 h / Ambient temperature
2: 70 percent / Ph3P, Et3N / CH2Cl2 / 2 h / Ambient temperature
View Scheme
参考文献
Corsaro, A.; Tarantello, M.; Purrello, G.
Tetrahedron Letters, 1981 , vol. 22, # 34 p. 3305 - 3308
反应条件
1: 76 percent / benzene / standing overnight
2: 95 percent / H2S (gas) / ethanol / 1.) -60 - 50 deg C, 13 hrs., 2.) -15 deg C, overnight
3: 68.3 percent / hydrazine hydrate (50 percent), aq.potassium hydroxide (1 N) / -6 - 0 °C
4: 86.8 percent / ethanol / 4 h / Heating
View Scheme
参考文献
Tomchin, A.B.
Journal of Organic Chemistry USSR (English Translation), 1981 , vol. 17, p. 504 - 510
Zhurnal Organicheskoi Khimii, 1981 , vol. 17, # 3 p. 589 - 595
参考文献
Sundberg, Richard J.; Walters, Claudia Powers; Bloom, Jonathan D.
Journal of Organic Chemistry, 1981 , vol. 46, # 18 p. 3730 - 3732
