5-(甲氧基甲烯基)-2,2-二甲基-1,3-二氧己环-4,6-二酮合成路线 （共 30 条）
反应条件
in acetonitrile T=20°C; 0.25 h;
参考文献
Hill, Lawrence; Imam, S. Haider; McNab, Hamish; O'Neill, William J.
Synlett, 2009 , # 11 p. 1847 - 1851
参考文献
Molnar, Annamaria; Faigl, Ferenc; Podanyi, Benjamin; Finta, Zoltan; Balazs, Laszlo; Hermecza, Istvan
Heterocycles, 2009 , vol. 78, # 10 p. 2477 - 2488
反应条件
1: in diphenylether T=70°C; 0.5 h; 2: in diphenylether; biphenyl T=220°C; 1 h; 3: With N-ethyl-N,N-diisopropylamine; trichlorophosphate T=100°C; 1 h;
参考文献
EP1724268 A1, ;
Page/Page column 60-61 ;
反应条件
1: in isopropyl alcohol 1 h; Reflux; 2: T=210°C; 1 h;
参考文献
TAIHO PHARMACEUTICAL CO., LTD.; Kitade, Makoto; Yamashita, Satoshi; Ohkubo, Shuichi
Patent: US2013/296320 A1, 2013 ;
Location in patent: Paragraph 0308 ;
反应条件
in acetonitrile T=20°C; 0.5 h;
参考文献
McNab, Hamish; Monahan, Lilian C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1988 , p. 863 - 868
反应条件
in acetonitrile T=20°C; 0.25 h;
参考文献
Hill, Lawrence; Imam, S. Haider; McNab, Hamish; O'Neill, William J.
Synlett, 2009 , # 11 p. 1847 - 1851
反应条件
6-methylpiperid-2-one in acetonitrile Reflux;
参考文献
McNab, Hamish; Morrow, Mark; Parsons, Simon; Shannon, David A.; Withell, Kirsti
Organic and Biomolecular Chemistry, 2009 , vol. 7, # 23 p. 4936 - 4942
反应条件
in acetonitrile 2 h; Heating;
参考文献
Derbyshire, Paul A.; Hunter, Gordon A.; McNab, Hamish; Monahan, Lilian C.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1993 , # 17 p. 2017 - 2026
反应条件
in diphenylether; biphenyl T=80 - 220°C; 4 h;
参考文献
KIRIN BEER KABUSHIKI KAISHA
Patent: EP1724268 A1, 2006 ;
Location in patent: Page/Page column 41-42 ;
反应条件
ytterbium(III) triflate in nitromethane T=100°C; 1.5 h;
参考文献
Fillion, Eric; Dumas, Aaron M.; Kuropatwa, Bryan A.; Malhotra, Neil R.; Sitler, Tamsyn C.
Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 409 - 412
