5-(甲氧基甲烯基)-2,2-二甲基-1,3-二氧己环-4,6-二酮合成路线 （共 30 条）
参考文献
Fillion, Eric; Dumas, Aaron M.; Hogg, Sylvia A.
Journal of Organic Chemistry, 2006 , vol. 71, # 26 p. 9899 - 9902
反应条件
ytterbium(III) triflate in nitromethane T=100°C; 1.5 h;
参考文献
Fillion, Eric; Dumas, Aaron M.; Kuropatwa, Bryan A.; Malhotra, Neil R.; Sitler, Tamsyn C.
Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 409 - 412
反应条件
1: in tetrahydrofuran
T=0 - 20°C;
2: With hydrogenchloride
0.5 h;
参考文献
Fillion, Eric; Fishlock, Dan; Wilsily, Ashraf; Goll, Julie M.
Journal of Organic Chemistry, 2005 , vol. 70, # 4 p. 1316 - 1327
反应条件
potassium tert-butylate in methanol
1.) 30 min at 0 deg C; 2.) 30 min at 0 deg C then 2 h at room temp.;
参考文献
Wessig, P.; Schwarz, J.
Monatshefte fuer Chemie, 1995 , vol. 126, # 1 p. 99 - 102
反应条件
1: 2-Methoxy-5-nitro benzyl bromide With hydrogen; triethylamine; palladium hydroxide on carbon in N,N-dimethyl-formamide
T=20°C;
2: 5-(Methoxymethylene)-2,2-dimethyl-1,3-dioxane-4,6-dione in isopropyl alcohol
T=70°C; 0.5 h;
3: in diphenylether; biphenyl
T=220°C; 3 h;
参考文献
KIRIN BEER KABUSHIKI KAISHA
Patent: EP1724268 A1, 2006 ;
Location in patent: Page/Page column 63 ;
反应条件
1: in isopropyl alcohol
T=70°C; 0.5 h;
2: in diphenylether; biphenyl
T=220°C; 0.5 h;
3: With hydrogen; triethylamine; palladium 10 on activated carbon in N,N-dimethyl-formamide
T=20°C;
参考文献
KIRIN BEER KABUSHIKI KAISHA
Patent: EP1724268 A1, 2006 ;
Location in patent: Page/Page column 75-76 ;
反应条件
in acetonitrile
5 h; Ambient temperature;
参考文献
Hickson, Clare L.; Keith, Eileen M.; Martin, Jane C.; McNab, Hamish; Monahan, Lilian C.; Walkinshaw, Malcolm D.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1986 , p. 1465 - 1470
反应条件
triethylamine in isopropyl alcohol
T=70°C; 3 h; Product distribution / selectivity;
参考文献
KIRIN BEER KABUSHIKI KAISHA
Patent: EP1724268 A1, 2006 ;
Location in patent: Page/Page column 82-83; 98 ;
反应条件
ytterbium(III) triflate in nitromethane
T=100°C; 1.5 h;
参考文献
Fillion, Eric; Dumas, Aaron M.; Kuropatwa, Bryan A.; Malhotra, Neil R.; Sitler, Tamsyn C.
Journal of Organic Chemistry, 2006 , vol. 71, # 1 p. 409 - 412
反应条件
(i) (pyrolysis), (ii) /BRN= 605631/; Multistep reaction;
参考文献
Baxter,G.J. et al.
Australian Journal of Chemistry, 1977 , vol. 30, p. 459 - 463
