6-溴吡啶并[2,3-D]嘧啶-4(1H)-酮合成路线 （共 4 条）
反应条件
in N,N-dimethyl-formamide 16 h; Heating / reflux;
参考文献
WO2008/23161 A1, ;
Page/Page column 111-112 ;
WO 2008/023161 A1
反应条件
T=150°C; 0.5 h; Microwave irradiation;
参考文献
Zhang, Dengyou; Ai, Jing; Liang, Zhongjie; Li, Chunpu; Peng, Xia; Ji, Yinchun; Jiang, Hualiang; Geng, Meiyu; Luo, Cheng; Liu, Hong
Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 17 p. 5169 - 5180
反应条件
1: acetic acid; bromine / 0.5 h / 20 °C 2: 0.5 h / 150 °C / |Microwave irradiation View Scheme
参考文献
Bioorganic and Medicinal Chemistry, , vol. 20, # 17 p. 5169 - 5180
反应条件
pyridine; trichlorophosphate in toluene T=180°C; P=225.023 - 1050.11 Torr; 2 h;
参考文献
Sun, Zhihua; Wang, Han; Wen, Kun; Li, Ya; Fan, Erkang
Journal of Organic Chemistry, 2011 , vol. 76, # 10 p. 4149 - 4153
