氘代3-氨基-5-吗啉-4-甲基-恶唑-2-啉酮合成路线 （共 36 条）
反应条件
1-piperidinylphosphorous dichloride; lithium in tetrahydrofuran 13 h; Inert atmosphereReflux;
参考文献
Askham, Fredric R.; Stanley, George G.; Marques, Edward C.
Journal of the American Chemical Society, 1985 , vol. 107, # 25 p. 7423 - 7431
反应条件
P4; Ti(N[t-Bu](3,5-Me2C6H3))3 in benzene T=20°C; Inert atmosphere;
参考文献
Cossairt, Brandi M.; Cummins, Christopher C.
New Journal of Chemistry, 2010 , vol. 34, # 8 p. 1533 - 1536
反应条件
1: phosphorous With sodium; potassium in ethylene glycol dimethyl ether 24 h; RefluxInert atmosphere; 2: chloro-trimethyl-silane T=30°C; Inert atmosphere;
参考文献
Gary, Dylan C.; Cossairt, Brandi M.
Chemistry of Materials, 2013 , vol. 25, # 12 p. 2463 - 2469
反应条件
in tetrahydrofuran T=-70 - 20°C; 25 h;
参考文献
Wisniewska, Aleksandra; Lapczuk-Krygier, Agnieszka; Baranowska, Katarzyna; Chojnacki, Jaroslaw; Matern, Eberhard; Pikies, Jerzy; Grubba, Rafal
Polyhedron, 2013 , vol. 55, p. 45 - 48
反应条件
in tetrahydrofuran T=-70 - 20°C;
参考文献
Wisniewska, Aleksandra; Lapczuk-Krygier, Agnieszka; Baranowska, Katarzyna; Chojnacki, Jaroslaw; Matern, Eberhard; Pikies, Jerzy; Grubba, Rafal
Polyhedron, 2013 , vol. 55, p. 45 - 48
反应条件
1,2-diiododisilane in pentane T=-75°C;
参考文献
Hassler, K.; Katzenbeisser, U.
Journal of Organometallic Chemistry, 1990 , vol. 399, # 3 p. C18 - C20
参考文献
Journal of the American Chemical Society, , vol. 81, p. 6273
反应条件
in tetrahydrofuran; pentane byproducts: LiCl; (N2), added at 0°C, stirred for 2 h at 0°C, stirred for 5 h at 20°C; filtered, solvent removed in vacuo, recrystallized from pentane at 0°C, elem. anal.;
参考文献
Chemische Berichte, , vol. 124, p. 1497 - 1504
反应条件
in benzene byproducts: LiCl; under N2 or Ar or in vac., reflux for 4 h; cooled to room temp., filtered, solvent evapd. from the filtrate, warmed in vac. to 50°C (removal of P(SiMe3)3); elem. anal.;
参考文献
Koelle, Peter; Linti, Gerald; Noeth, Heinrich; Wood, Gary L.; Narula, Chaitanya K.; Paine, Robert T.
Chemische Berichte, 1988 , vol. 121, p. 871 - 880
反应条件
in benzene byproducts: LiCl; under N2 or Ar or in vac., 25°C; filtered, evapn. of solvent, P(SiMe3)3 removed by gentle warming; elem. anal.;
参考文献
Koelle, Peter; Linti, Gerald; Noeth, Heinrich; Wood, Gary L.; Narula, Chaitanya K.; Paine, Robert T.
Chemische Berichte, 1988 , vol. 121, p. 871 - 880
