tetra-n-butylammonium tetrafluoroborate in N,N-dimethyl-formamide T=-20°C; Electrochemical reaction;

1: With 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide T=20°C; 2: With hydrogenchloride in methanol Title compound not separated from byproducts;

tetra-n-butylammonium tetrafluoroborate in acetonitrile T=-20°C; Electrochemical reaction; Product distribution; Further Variations:SolventsTemperatures;

1: With 1,8-diazabicyclo[5.4.0]undec-7-ene in N,N-dimethyl-formamide T=20°C; Michael addition; 2: With hydrogenchloride in methanol; water T=70°C; Hydrolysis; 3: With cation-exchange resin Dowex; water Cyclization; ring cleavage; hydrolysis;

1: methyllithium With copper(l) iodide in tetrahydrofuran; diethyl ether T=-40°C; 0.333333 h; 2: (4R)-N-[(2E)-3-phenylprop-2-enoyl]-4-phenyl-1,3-oxazolidin-2-one With trimethylsilyl iodide in tetrahydrofuran; diethyl ether T=-78°C; 4 h; Title compound not separated from byproducts;

1: 1.) Mg, 2.) CuBr*Me2S, Me2S / 1) THF, reflux, 15 min; 2) THF, -50 deg C, 3 min; 3) THF, 10 deg C, 2 h 2: 90 percent / LiOH, H2O2 / tetrahydrofuran; H2O 3: 1.) SOCl2 / 1) benzene, 50 deg C, 50 min; 2) ether, rt, 1.5 h 4: 1.) LiAlH4, 2.) H2 / 2.) Pd/C / 1) ether, rt, overnight; 2) MeOH, 1 atm, rt, overnight View Scheme