4-(吲哚-3-基)丁酸甲酯合成路线 （共 5 条）
反应条件
1: LiAlH4 / tetrahydrofuran / 0.67 h 2: 58 percent / K2CO3, CuI, ZnO, 1-methyl-2-pyrrolidinone / 6 h / 155 °C 3: 95 percent / triethylamine / CH2Cl2 / 1.5 h / 10 - 20 °C 4: K2CO3, methyl isobutyl ketone / 16 h / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 38, # 11 p. 1998 - 2008
反应条件
hydrazine hydrate in ethanol Heating;
参考文献
Demange, Luc; Boeglin, Damien; Moulin, Aline; Mousseaux, Delphine; Ryan, Joanne; Berge, Gilbert; Gagne, Didier; Heitz, Annie; Perrissoud, Daniel; Locatelli, Vittorio; Torsello, Antonio; Galleyrand, Jean-Claude; Fehrentz, Jean-Alain; Martinez, Jean
Journal of Medicinal Chemistry, 2007 , vol. 50, # 8 p. 1939 - 1957
反应条件
1: ethanol; aqueous N2H4 / 150 °C 2: NaNO2; aqueous acetic acid / Erwaermen des Reaktionsprodukts mit H2O 4: N2H4; aqueous ethanol View Scheme
参考文献
Jackson; Manske
Journal of the American Chemical Society, 1930 , vol. 52, p. 5029,5031
反应条件
1: ethanol; aqueous N2H4 / 150 °C 2: NaNO2; aqueous acetic acid / Erwaermen des Reaktionsprodukts mit H2O View Scheme
参考文献
Journal of the American Chemical Society, , vol. 52, p. 5029,5031
反应条件
1: 83 percent / ammonia / methanol / 48 h / 20 °C
2: LiAlH4 / tetrahydrofuran / 24 h / 20 °C
View Scheme
参考文献
Doernyei, Gabor; Incze, Maria; Kajtar-Peredy, Maria; Szantay, Csaba
Collection of Czechoslovak Chemical Communications, 2002 , vol. 67, # 11 p. 1669 - 1680
