反应条件
1: BF3*OEt2 / 12 h / Ambient temperature
2: anhydrous potassium carbonate / butan-2-one / 24 h / Heating
3: 89 percent / N,N,N',N'-tetramethylethylenediamine / 12 h / 200 °C
4: 100 percent / camphorsulfonic acid (CSA) / benzene / 12 h / Heating
5: 1.) sec-BuLi / 1.) THF, -78 deg C
6: 35 percent / NaH / dimethylsulfoxide / 24 h / 22 °C
7: H2 / 10percent Pd/C / dioxane / 0.75 h / 22 °C / 760 Torr
8: camphorsulfonic acid (CSA) / CH2Cl2; tetrahydrofuran / 5 h / 0 °C
9: 1.) LDA / 1.) THF, hexane, -78 deg C, 15 min, 2.) a) 30 min, b) 0 deg C, 1 h
10: 58 percent / camphorsulfonic acid (CSA) / methanol; benzene / 0.33 h / Heating
View Scheme
参考文献
Williams, David R.; Sit, Sing-Yuen
Journal of Organic Chemistry, 1982 , vol. 47, # 15 p. 2846 - 2851
