2,4-二氨基-6-氯嘧啶合成路线 （共 36 条）
反应条件
sulfuric acid in water
3 h; Heating;
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
反应条件
N-chloro-succinimide in methanol
T=20°C; 1.5 h;
参考文献
Cowden, William B.; Jacobsen, Noel W.
Australian Journal of Chemistry, 1984 , vol. 37, # 6 p. 1195 - 1201
反应条件
sulfuric acid; sodium sulfite in water
1.75 h; Heating;
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
反应条件
sulfuric acid; sodium sulfite in water
1.5 h; Heating;
参考文献
Okafor; Steenberg; Buckley
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 1 p. 302 - 318
参考文献
Koppel et al.
Journal of the American Chemical Society, 1959 , vol. 81, p. 3046,3050
反应条件
1: With sulfuric acid; nitric acid
T=35°C; 0.5 h;
2: With ammonia in water
T=-10°C;
参考文献
Marchetti, Francesco; Cano, Celine; Curtin, Nicola J.; Golding, Bernard T.; Griffin, Roger J.; Haggerty, Karen; Newell, David R.; Parsons, Rachel J.; Payne, Sara L.; Wang, Lan Z.; Hardcastle, Ian R.
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 10 p. 2397 - 2407
