反应条件
1: 3,4,5,6-Tetrahydro-2H-pyran-4-carboxylic acid With 1,1'-carbonyldiimidazole in dichloromethane 2 h; 2: O,N-dimethyl-hydroxylamine hydrochloride in dichloromethane 3 h;
参考文献
ELI LILLY AND COMPANY; BEIGHT, Douglas, Wade; BURKHOLDER, Timothy, Paul; CLAYTON, Joshua, Ryan; EGGEN, MariJean; HENRY, Kenneth, James, Junior; JOHNS, Deidre, Michelle; PARTHASARATHY, Saravanan; PEI, Huaxing; REMPALA, Mark, Edward; SAWYER, Jason, Scott
Patent: WO2011/50016 A1, 2011 ;
Location in patent: Page/Page column 100 ;
WO 2011/050016 A1