(1R)-4-叠氮基-1-羧基-1-丁烷铵氯化物合成路线 （共 6 条）
反应条件
1: H2 / Pd/C / ethyl acetate / 16 h / 2068.59 Torr 2: 382 mg / K2CO3; aq. CuSO4; TfN3 / CH2Cl2; methanol View Scheme
参考文献
Link, A. James; Vink, Mandy K. S.; Tirrell, David A.
Journal of the American Chemical Society, 2004 , vol. 126, # 34 p. 10598 - 10602
反应条件
boron tribromide in dichloromethane T=-10 - 20°C; 3 h;
参考文献
Roth, Stefanie; Thomas, Neil R.
Synlett, 2010 , # 4 art. no. D28009ST, p. 607 - 609
反应条件
trifluoromethanesulfonyl azide; potassium carbonate; copper(II) sulfate in methanol; dichloromethane
参考文献
Link, A. James; Vink, Mandy K. S.; Tirrell, David A.
Journal of the American Chemical Society, 2004 , vol. 126, # 34 p. 10598 - 10602
反应条件
hydrogenchloride in water T=20°C; 6 h;
参考文献
Isaad, Alexandra Le Chevalier; Barbetti, Francesca; Rovero, Paolo; D'Ursi, Anna Maria; Chelli, Mario; Chorev, Michael; Papini, Anna Maria
European Journal of Organic Chemistry, 2008 , # 31 p. 5308 - 5314
反应条件
1: NaN3 / various solvent(s) / 72 h / Ambient temperature 2: 1N aqueous HCl / tetrahydrofuran / 24 h / Ambient temperature 3: LiOH*H2O / tetrahydrofuran; H2O / 24 h / Ambient temperature View Scheme
参考文献
Oppolzer; Moretti; Zhou
Helvetica Chimica Acta, 1994 , vol. 77, # 8 p. 2363 - 2380
反应条件
sodium hydroxide in 1,4-dioxane; water T=20°C; pH=8 - 9; 2.5 h;
参考文献
Isaad, Alexandra Le Chevalier; Barbetti, Francesca; Rovero, Paolo; D'Ursi, Anna Maria; Chelli, Mario; Chorev, Michael; Papini, Anna Maria
European Journal of Organic Chemistry, 2008 , # 31 p. 5308 - 5314
