(R)-4,5,5-三苯基-2-恶唑烷酮合成路线 (共 5 条)
反应条件
triethylamine in dichloromethane T=0°C; 1 h;
参考文献
Akiba, Toshifumi; Tamura, Osamu; Hashimoto, Masaru; Kobayashi, Yuko; Katoh, Tadashi; et al.
Tetrahedron, 1994 , vol. 50, # 13 p. 3905 - 3914
反应条件
potassium tert-butylate in tetrahydrofuran T=0°C; 0.5 h;
参考文献
Bull, Steven D.; Davies, Stephen G.; Jones, Simon; Sanganee, Hitesh J.
Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 4 p. 387 - 398
反应条件
1: SOCl2 / 24 h / Ambient temperature 2: NaHCO3 / ethanol / 48 h / Ambient temperature 3: 1.) Mg / 1.) THF, reflux, 2.) THF, r.t., 48 h 4: 81 percent / t-BuOK / tetrahydrofuran / 0.5 h / 0 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 4 p. 387 - 398
反应条件
1: NaHCO3 / ethanol / 48 h / Ambient temperature 2: 1.) Mg / 1.) THF, reflux, 2.) THF, r.t., 48 h 3: 81 percent / t-BuOK / tetrahydrofuran / 0.5 h / 0 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 4 p. 387 - 398
反应条件
1: 1.) Mg / 1.) THF, reflux, 2.) THF, r.t., 48 h 2: 81 percent / t-BuOK / tetrahydrofuran / 0.5 h / 0 °C View Scheme
参考文献
Journal of the Chemical Society - Perkin Transactions 1, , # 4 p. 387 - 398