反应条件
1: 79 percent / I2, Ph3P, imidazole / CH2Cl2 / 5 h / 20 °C 2: 81 percent / 1.) BuLi / 1.) hexane, THF, -70 degC to 0 degC, 3 h, 2a.) THF, -78 degC, 1 h, 2b.) room temp., 12 h 3: 78 percent / HgCl2, HgO / methanol; H2O / 3 h / Heating 4: 87 percent / 1.) BuLi / 1.) hexane, THF, -70 degC to room temp., 3 h, 2.a) THF, -70 degC, 1 h, 2b.) room temp., overnight 5: 93 percent / 1.) BuLi / 1.) hexane, THF, HMPA, -78 degC to room temp. in 3 h, 2a.) -78 degC, 1 h, 2b.) room temp. overnight 6: 82 percent / HgCl2, HgO / methanol; H2O / a.) room temp., 5 h, b.) 50 degC, 1 h View Scheme
