S-(-)-2-甲基-1-丁醇合成路线 （共 117 条）
反应条件
1: 47 percent / (PPh3)2PdCl2, CuI / triethylamine / 78 h / Ambient temperature 2: 1.) KMnO4, 2.) LiAlH4 / 1.) acetone, 2.) diethyl ether, reflux, 5 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 25 p. 4887 - 4891
反应条件
Saccharomyces cerevisiae; [14C]-Sucrose in water T=30°C; 18 h;
参考文献
Ferraboschi, Patrizia; Grisenti, Paride; Casati, Rosangela; Fiecchi, Alberto; Santaniello, Enzo
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 1743 - 1748
反应条件
1: 87 percent / (PPh3)2PdCl2, CuI / triethylamine / 78 h / Ambient temperature 2: 1.) KMnO4, 2.) LiAlH4 / 1.) acetone, 2.) diethyl ether, reflux, 5 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 48, # 25 p. 4887 - 4891
反应条件
lithium aluminium tetrahydride Inert atmosphere;
参考文献
Xu, Shiqing; Lee, Ching-Tien; Wang, Guangwei; Negishi, Ei-Ichi
Chemistry - An Asian Journal, 2013 , vol. 8, # 8 p. 1829 - 1835
反应条件
lithium aluminium tetrahydride
参考文献
Tyrrell, Elizabeth; Skinner, George A.; Janes, John; Milsom, Greig
Synlett, 2002 , # 7 p. 1073 - 1076
反应条件
diisobutylaluminum hydride in tetrahydrofuran; hexane T=-20°C; 1 h;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 897 - 903
反应条件
1: 8 h / 0 °C / asymmetric hydrolysis with Lipase P, acetate buffer, pH 5 2: H2 / PtO2 / ethyl acetate / 2 h / 760 Torr / Ambient temperature 3: pyridine / 12 h / 0 °C 4: LiAlH4 / diethyl ether / 12 h / Heating View Scheme
参考文献
Liebigs Annalen der Chemie, , # 10 p. 1057 - 1065
反应条件
1: 95 percent / pyridine / 3 h / Ambient temperature 2: 97 percent / H2 / Lindlar / ethyl acetate / 24 h / Ambient temperature 3: 8 h / 0 °C / asymmetric hydrolysis with Lipase P, acetate buffer, pH 5 4: H2 / PtO2 / ethyl acetate / 2 h / 760 Torr / Ambient temperature 5: pyridine / 12 h / 0 °C 6: LiAlH4 / diethyl ether / 12 h / Heating View Scheme
参考文献
Liebigs Annalen der Chemie, , # 10 p. 1057 - 1065
反应条件
1: 97 percent / H2 / Lindlar / ethyl acetate / 24 h / Ambient temperature 2: 8 h / 0 °C / asymmetric hydrolysis with Lipase P, acetate buffer, pH 5 3: H2 / PtO2 / ethyl acetate / 2 h / 760 Torr / Ambient temperature 4: pyridine / 12 h / 0 °C 5: LiAlH4 / diethyl ether / 12 h / Heating View Scheme
参考文献
Liebigs Annalen der Chemie, , # 10 p. 1057 - 1065
反应条件
1: H2 / PtO2 / ethyl acetate / 2 h / 760 Torr / Ambient temperature 2: pyridine / 12 h / 0 °C 3: LiAlH4 / diethyl ether / 12 h / Heating View Scheme
参考文献
Liebigs Annalen der Chemie, , # 10 p. 1057 - 1065
