(R)-2-甲基丁烷-1,4-二胺合成路线 （共 11 条）
反应条件
1: 70 percent / sodium acetate, H2 / 10percent Pd/C / ethanol / 2 h / 2585.7 Torr 2: 42 percent / 80percent hydrazine hydrate, KOH / ethane-1,2-diol / 1.5 h / 200 °C 3: 1.) Na2CO3, hydroxylamine hydrochloride, 2.) Na, EtOH / 1.) ethanol, reflux, 168 h, 2.) reflux, 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 403 - 407
反应条件
1: 90 percent / 10percent Pd/C / ethanol / 16 h / 2585.7 Torr 2: 73 percent / KOH / ethane-1,2-diol / 200 °C 3: 1.) Na2CO3, hydroxylamine hydrochloride, 2.) Na, EtOH / 1.) ethanol, reflux, 168 h, 2.) reflux, 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 403 - 407
反应条件
1: hydrazine / 2 h / Heating 2: pyridine / 0.5 h / 20 °C 3: 15 percent / sodium carbonate / ethane-1,2-diol / 0.08 h / 170 °C 4: 42 percent / 80percent hydrazine hydrate, KOH / ethane-1,2-diol / 1.5 h / 200 °C 5: 1.) Na2CO3, hydroxylamine hydrochloride, 2.) Na, EtOH / 1.) ethanol, reflux, 168 h, 2.) reflux, 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 403 - 407
反应条件
1: pyridine / 0.5 h / 20 °C 2: 15 percent / sodium carbonate / ethane-1,2-diol / 0.08 h / 170 °C 3: 42 percent / 80percent hydrazine hydrate, KOH / ethane-1,2-diol / 1.5 h / 200 °C 4: 1.) Na2CO3, hydroxylamine hydrochloride, 2.) Na, EtOH / 1.) ethanol, reflux, 168 h, 2.) reflux, 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 403 - 407
反应条件
1: 73 percent / KOH / ethane-1,2-diol / 200 °C 2: 1.) Na2CO3, hydroxylamine hydrochloride, 2.) Na, EtOH / 1.) ethanol, reflux, 168 h, 2.) reflux, 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 403 - 407
反应条件
1: 42 percent / 80percent hydrazine hydrate, KOH / ethane-1,2-diol / 1.5 h / 200 °C 2: 1.) Na2CO3, hydroxylamine hydrochloride, 2.) Na, EtOH / 1.) ethanol, reflux, 168 h, 2.) reflux, 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 403 - 407
反应条件
1: 15 percent / sodium carbonate / ethane-1,2-diol / 0.08 h / 170 °C 2: 42 percent / 80percent hydrazine hydrate, KOH / ethane-1,2-diol / 1.5 h / 200 °C 3: 1.) Na2CO3, hydroxylamine hydrochloride, 2.) Na, EtOH / 1.) ethanol, reflux, 168 h, 2.) reflux, 4 h View Scheme
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 403 - 407
反应条件
lithium aluminium tetrahydride in tetrahydrofuran 27 h; Heating;
参考文献
Kojima, Masaaki; Morita, Ken'ichi; Fujita, Junnosuke
Bulletin of the Chemical Society of Japan, 1981 , vol. 54, # 10 p. 2947 - 2955
反应条件
1: methanolic NH3 / 144 h / Ambient temperature 2: 10 g / LiAlH4 / tetrahydrofuran / 27 h / Heating View Scheme
参考文献
Bulletin of the Chemical Society of Japan, , vol. 54, # 10 p. 2947 - 2955
反应条件
ethanol; hydroxylamine hydrochloride; sodium; sodium carbonate 1.) ethanol, reflux, 168 h, 2.) reflux, 4 h; Multistep reaction;
参考文献
Journal of Organic Chemistry, , vol. 53, # 2 p. 403 - 407
