tetrabutyl ammonium fluoride in tetrahydrofuran 0.0833333 h; reactions of derivatives under var. conditions; Product distribution;

<b>Multi-step reaction with 4 steps<br /> </b>1: 60 percent / fuming HNO₃, 96percent H₂SO₄ / acetic anhydride / 1 h / -20 &deg;C<br />2: 77 percent / conc. aq. HCl/MeOH / 2 h / 50 - 60 &deg;C<br />3: 68 percent / DCC/DMAP / CH₂Cl₂ / 2 h, 0 deg C and room t. overnight<br />4: 76 percent / LiOH*H₂O / acetone; H₂O / 2 h / 0 deg C, 2 h and 0,5 h, room t.<br /> <br /> &nbsp;

<b>Multi-step reaction with 5 steps<br /> </b>1: 60 percent / AlCl₃ / CH₂Cl₂ / in ice bath, 30 min and 1 h, room t.<br />2: 60 percent / fuming HNO₃, 96percent H₂SO₄ / acetic anhydride / 1 h / -20 &deg;C<br />3: 77 percent / conc. aq. HCl/MeOH / 2 h / 50 - 60 &deg;C<br />4: 68 percent / DCC/DMAP / CH₂Cl₂ / 2 h, 0 deg C and room t. overnight<br />5: 76 percent / LiOH*H₂O / acetone; H₂O / 2 h / 0 deg C, 2 h and 0,5 h, room t.<br /> <br /> &nbsp;