1,4-二溴-2,3-二氟苯合成路线 （共 4 条）
反应条件
bromine T=0 - 58°C; Inert atmosphere;
参考文献
Liu, Xuncheng; Cai, Ping; Chen, Zhenhui; Zhang, Lianjie; Zhang, Xiaofei; Sun, Jiangman; Wang, Haitao; Chen, Junwu; Peng, Junbiao; Chen, Hongzheng; Cao, Yong
Polymer (United Kingdom), 2014 , vol. 55, # 7 p. 1707 - 1715
反应条件
bromine T=0 - 58°C; 2 h;
参考文献
Billedeau, Roland Joseph; Sweeney, Zachary Kevin
Patent: US2009/170856 A1, 2009 ;
Location in patent: Page/Page column 26 ;
反应条件
1: lithium diisopropyl amide / tetrahydrofuran; hexane / 1 h / -78 - -50 °C 2: bromine / 2 h / 0 - 58 °C View Scheme
参考文献
Journal of the American Chemical Society, , vol. 133, # 23 p. 9005 - 9013
反应条件
1: 2,3-difluoro-1,4-dibromobenzene With isopropylmagnesium chloride; lithium chloride in tetrahydrofuran
T=-35 - 40°C; 2 h;
2: N,N-dimethyl-formamide in tetrahydrofuran
T=-30 - 15°C; 3.5 h;
参考文献
Roche Palo Alto LLC
Patent: US2006/25462 A1, 2006 ;
Location in patent: Page/Page column 11; 21 ;
