1.1: 92 percent / K2CO3 / acetone / 48 h / Heating 2.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C 2.2: hexane; tetrahydrofuran / -78 - 20 °C 3.1: 100 percent / 10 percent aq. HCl / 1 h / 20 °C View Scheme

1.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C 1.2: hexane; tetrahydrofuran / -78 - 20 °C 2.1: 100 percent / 10 percent aq. HCl / 1 h / 20 °C 3.1: 100 percent / 10 percent aq. H2O2 / diethyl ether / 2.5 h / Heating 4.1: 92 percent / K2CO3 / acetone / 48 h / Heating 5.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C 5.2: hexane; tetrahydrofuran / -78 - 20 °C 6.1: 100 percent / 10 percent aq. HCl / 1 h / 20 °C View Scheme

1.1: 92 percent / K2CO3 / acetone / 48 h / Heating 2.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C 2.2: hexane; tetrahydrofuran / -78 - 20 °C 3.1: 100 percent / 10 percent aq. HCl / 1 h / 20 °C View Scheme

1.1: 100 percent / 10 percent aq. H2O2 / diethyl ether / 2.5 h / Heating 2.1: 92 percent / K2CO3 / acetone / 48 h / Heating 3.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C 3.2: hexane; tetrahydrofuran / -78 - 20 °C 4.1: 100 percent / 10 percent aq. HCl / 1 h / 20 °C View Scheme

1.1: n-butyllithium / hexane; tetrahydrofuran / 2.5 h / -78 °C 1.2: hexane; tetrahydrofuran / -78 - 20 °C 2.1: 100 percent / 10 percent aq. HCl / 1 h / 20 °C View Scheme