N-丁-3-烯基氨基甲酸叔丁酯合成路线 （共 7 条）
反应条件
triethylamine in dichloromethane T=20°C; 18 h; Cooling with ice;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; BOY, Kenneth M.; GUERNON, Jason M.; MACOR, John E.; THOMPSON III, Lorin A.; WU, Yong-Jin; ZHANG, Yunhui
Patent: WO2012/9309 A1, 2012 ;
Location in patent: Page/Page column 56 ;
WO 2012/009309 A1
反应条件
trifluoroacetic acid in dichloromethane T=20°C; 0.0833333 h;
参考文献
UNIVERSITY OF WOLLONGONG
Patent: WO2006/74501 A1, 2006 ;
Location in patent: Page/Page column 209 ;
反应条件
triethylamine in dichloromethane T=0 - 20°C; Inert atmosphere;
参考文献
Pavlyuk, Oksana; Teller, Henrik; McMills, Mark C.
Tetrahedron Letters, 2009 , vol. 50, # 23 p. 2716 - 2718
反应条件
triethylamine in dichloromethane T=0 - 20°C; 15 h; Inert atmosphere;
参考文献
Combettes, Lorraine E.; Schuler, Marie; Patel, Rakesh; Bonillo, Baltasar; Odell, Barbara; Thompson, Amber L.; Claridge, Tim D. W.; Gouverneur, Veronique
Chemistry - A European Journal, 2012 , vol. 18, # 41 p. 13126 - 13132
反应条件
1: 4-azido-1-butene With lithium aluminium tetrahydride in diethyl ether 2: di-tert-butyl dicarbonate in diethyl ether; water
参考文献
Hu, Xubo; Nguyen, Kiet T.; Jiang, Vernon C.; Lofland, Denene; Moser, Heinz E.; Pei, Dehua
Journal of Medicinal Chemistry, 2004 , vol. 47, # 20 p. 4941 - 4949
反应条件
1: 93 percent / cesium carbonate; lithium iodide / butan-2-one / 48 h / Heating 2: 96 percent / TFA / CH2Cl2 / 0.08 h / 20 °C View Scheme
参考文献
Boyle, Timothy P.; Bremner, John B.; Coates, Jonathan A.; Keller, Paul A.; Pyne, Stephen G.
Tetrahedron, 2005 , vol. 61, # 30 p. 7271 - 7276
反应条件
copper(l) chloride T=80°C; Inert atmosphere;
参考文献
Walker, P. Ross; Campbell, Craig D.; Suleman, Abid; Carr, Greg; Anderson, Edward A.
Angewandte Chemie - International Edition, 2013 , vol. 52, # 35 p. 9139 - 9143
Angew. Chem., 2013 , vol. 125, # 36 p. 9309 - 9313
